Abdullah Badawi declared an end to the economic legacy and grandiose projects of his predecessor, Mahathir Mohamad, during the 57th UMNO General Assembly. He told delegates that he would not pursue the economic strategies adopted two decades ago by Mahathir.

Badawi is a former student of Bukit Mertajam High School. He studied at MBS (Methodist Boy's School) Penang for his 6th form. Badawi obtained a Bachelor of Arts degree in Islamic Studies from the University of Malaya in 1964.

After graduating from the University of Malaya, he joined the Malaysian Administrative and Diplomatic Corps (the formal term for the civil service). He served as Director of Youth at the Ministry of Youth and Sport as well as Secretary of the National Operations Council (MAGERAN). He resigned in 1978 to become the member of parliament for his constituency of Kepala Batas in northern Seberang Perai (which had also been represented by his father).

When UMNO (Baru) was formed in February 1988, Mahathir, the UMNO President and Prime Minister, brought Abdullah into the pro tem committee of UMNO (Baru) as the vice-president. In 1990, Abdullah retained his seat as vice-president. During the Cabinet reshuffle in 1991, Mahathir brought him back into the Cabinet as Foreign Minister. He held this post until November 1999, when Syed Hamid Albar succeeded him. Even though he lost his vice presidency in the 1993 UMNO elections, he remained in the Cabinet and was appointed Minister of Foreign Affairs. Prior to 1998, he also served as Minister in the Prime Minister's Department, Minister of Education, Minister of Defence, and Minister of Foreign Affairs. He completed his probation when he was appointed Deputy Prime Minister of Malaysia and Minister of Home Affairs following the dismissal of Anwar Ibrahim.

After Deputy Prime Minister Anwar Ibrahim was dismissed, Prime Minister Mahathir Mohamad appointed Abdullah as Deputy Prime Minister in 1999. Abdullah went on to succeed Mahathir as Prime Minister in 2003.

Abdullah Badawi was heavily involved in foreign policy making. He was the chairman of the Organisation of the Islamic Conference since the start of his premiership in 2003. As of 2005, he was the chairman of the ASEAN. He also served as chairman of the Non-Aligned Movement from October 2003 until September 2006.

On 10 September 2004, Abdullah Badawi, as Finance Minister, presented his maiden budget, which was seen by many as maintenance-oriented as opposed to the growth policies emphasised by Mahathir.

In 2005, it was alleged that under Abdullah Badawi's administration, there had been a significant increase in cases of cronyism regarding the distribution of import permits for foreign-manufactured vehicles. Then Prime Minister Mahathir had called for an investigation of the issue. Later, Mahathir Mohamad criticised Abdullah for cancelling a number of development projects that the former had started, such as the construction of a bridge to replace the causeway linking Malaysia and Singapore.

On 6 June 2007, the Prime Minister's office announced Abdullah Badawi's marriage to Jeanne Abdullah. On 9 June, a private ceremony was conducted at the Prime Minister's residence, Seri Perdana, and attended by close relatives. Jeanne was formerly married to the younger brother of Abdullah Badawi's late wife. She was also a manager at the Seri Perdana residential complex and has two children from her previous marriage.

In June 2008, the Sabah Progressive Party, a member of the 14-party ruling Barisan Nasional coalition, said its two legislators in the federal parliament will move or back a motion of no-confidence against Abdullah.

In 2007 Prime Minister Abdullah Ahmad Badawi first called Malaysia an Islamic state. Earlier that month he had made another statement, saying Malaysia was neither a theocratic or secular state. A similar statement was made by Prime Minister on 12 March 2009, where he stated Malaysia was a "negara Islam". The Malaysian Chinese Association (MCA), a political group representing Malaysian Chinese, expressed reservations over this announcement. The MCA's position is that Malaysia is a fully secular state, and that the law transcends religion.