Anand Jain served on board of trustees of Mumbai Port Trust twice for two years each, and also on the Jawaharlal Nehru Port from April 1994 to March 1995. He is also a Director of the Rewas Port Limited, which is a Greenfield, mega scale port development project near Mumbai. The port would also serve as a primary gateway for the twin mega SEZs coming up in its vicinity: Viz; NMSEZ and MSEZ. The port in its first 5 yrs of operation aims to handle more than 50 Million tonnes of cargo. He has also promoted India's largest Real Estate private equity fund having raised over Rs. 32.86 billion from Retail and institutional Investors. He is an adviser to the Urban Infrastructure Real Estate Fund, which has raised US$500 Million from international Investors and along with the local participation of US$60 Million, the total fund size is US$560 Million.

According to an article published in The Economic Times in 2005, Anand Jain was first noted in Reliance in the mid-1980s, when he crushed the bear cartel led by Manu Manek, the then kingpin of Bombay Stock Exchange. Later, he emerged as a key figure in the running of the day-to-day operations of the Reliance group, particularly its Telecom venture Reliance Infocomm. In January 2005, Anil Ambani (brother of Mukesh Ambani) resigned as vice-chairman and Director of IPCL, citing his differences with Anand Jain. In June 2005, media reported that Jain would step down from the IPCL board, after a settlement was announced between the two Ambani brothers. However, in July 2005, it was reported that he has stayed on the IPCL board.

Anand Jain was No. 19 on the Forbes India's 40 richest list in 2007. He is regarded as a close associate of Mukesh Ambani.