It was during the reign of Elizabeth I that "Britannia" came to be viewed as a personification of Britain. In his 1576 General and rare memorials pertayning to the Perfect Arte of Navigation, John Dee used a frontispiece figure of Britannia kneeling by the shore beseeching Elizabeth I, to protect her empire by strengthening her navy.

With the death of Elizabeth in 1603 came the succession of her Scottish cousin, James VI, King of Scots, to the English throne. He became James I of England, and so brought under his personal rule the Kingdoms of England (and the dominion of Wales), Ireland and Scotland. On 20 October 1604, James VI and I proclaimed himself as "King of Great Brittaine, France and Ireland", a title that continued to be used by many of his successors. When James came to the English throne, some elaborate pageants were staged. One pageant performed on the streets of London in 1605 was described in Anthony Munday's Triumphs of Reunited Britannia:

Although the archetypical image of Britannia seated with a shield first appeared on Roman bronze coins of the 1st century AD struck under Hadrian, Britannia's first appearance on British coinage was on the farthing in 1672, though earlier pattern versions had appeared in 1665, followed by the halfpenny later the same year. The figure of Britannia was said by Samuel Pepys to have been modelled on Frances Teresa Stuart, the Future Duchess of Richmond, who was famous at the time for refusing to become the mistress of Charles II, despite the King's strong infatuation with her. Britannia then appeared on the British halfpenny coin throughout the rest of the 17th century and thereafter until 1936. The halfpennies issued during the reign of Queen Anne have Britannia closely resembling the queen herself. When the Bank of England was granted a charter in 1694, the Directors decided within days that the device for their official seal should represent 'Brittannia sitting on looking on a Bank of Mony' (sic). Britannia also appeared on the penny coin between 1797 and 1970, occasional issues such as the fourpence under william IV between 1836 and 1837, and on the 50 pence coin between 1969 and 2008. See "External Links" below for examples of all these coins and others.

In the 2nd century, Roman Britannia came to be personified as a goddess, armed with a trident and shield and wearing a Corinthian helmet. The name Britannia long survived the end of Roman rule in Britain in the 5th century and yielded the name for the island in most European and various other languages, including the English Britain and the modern Welsh Prydain. After centuries of declining use, the Latin form was revived during the English Renaissance as a rhetorical evocation of a British national identity. Especially following the Acts of Union in 1707, which joined the Kingdoms of England and Scotland, the personification of the martial Britannia was used as an emblem of British maritime power and unity, most notably in "Rule, Britannia!".

Neptune is shown symbolically passing his trident to Britannia in the 1847 fresco "Neptune Resigning to Britannia the Empire of the Sea" by william Dyce, a painting Victoria commissioned for her Osborne House on the Isle of Wight.

A figure of Britannia appeared on the "white fiver" (a five pound note printed in black and white) from 1855 for more than a century, until 1957.

The 25 cents fractional paper currency of the Dominion of Canada (1870, 1900 and 1923 respectively) all depict Britannia. The notes are no longer produced and usually not used as currency anymore, although they are still legal tender.

From 1928 "Britannia Series A" ten shilling and one pound notes were printed with a seated Britannia bearing both a spear and an olive branch.

The Roman conquest of the island began in AD 43, leading to the establishment of the Roman province known in Latin as Britannia. The Romans never successfully conquered the whole island, building Hadrian's Wall as a boundary with Caledonia, which covered roughly the territory of modern Scotland, although the whole of the boundary marked by Hadrian's Wall lies within modern-day Northern England. A southern part of what is now Scotland was occupied by the Romans for about 20 years in the mid-2nd century AD, keeping in place the Picts to the north of the Antonine Wall. People living in the Roman province of Britannia were called Britanni, or Britons. Ireland, inhabited by the Scoti, was never invaded and was called Hibernia. Thule, an island "six days' sail north of Britain, and [...] near the frozen sea", possibly Iceland, was also never invaded by the Romans.

The Emperor Claudius paid a visit while Britain was being conquered and was honoured with the agnomen Britannicus as if he were the conqueror; a frieze discovered at Aphrodisias in 1980 shows a bare breasted and helmeted female warrior labelled BRITANNIA, writhing in agony under the heel of the Emperor. She appeared on coins issued under Hadrian, as a more regal-looking female figure. Britannia was soon personified as a goddess, looking fairly similar to the goddess Minerva. Early portraits of the goddess depict Britannia as a beautiful young woman, wearing the helmet of a centurion, and wrapped in a white garment with her right breast exposed. She is usually shown seated on a rock, holding a spear, and with a spiked shield propped beside her. Sometimes she holds a standard and leans on the shield. On another range of coinage, she is seated on a globe above waves: Britain at the edge of the (known) world. Similar coin types were also issued under Antoninus Pius.

During the 1990s the term Cool Britannia (drawn from a humorous version by the Bonzo Dog Band of the song "Rule Britannia", with words by James Thomson [1700–1748], which is often used as an unofficial national anthem), was used to describe the contemporary United Kingdom. The phrase referred to the fashionable scenes of the era, with a new generation of pop groups and style magazines, successful young fashion designers, and a surge of new restaurants and hotels. Cool Britannia represented late-1990s Britain as a fashionable place to be.

Britannia also featured on the high value Great Britain definitive postage stamps issued during the reign of George V (known as 'seahorses') and is depicted on the £10 stamp first issued in 1993.

In the spring of 2008, the Royal Mint unveiled new coin designs "reflecting a more modern twenty-first century Britain" which do not feature the image of Britannia. This decision courted some controversy, with tabloid press campaigns, in particular that of the Daily Mail, launched to "save Britannia". The government has pointed out, however, that earlier-design 50p coins will remain in circulation for the foreseeable Future. Also Britannia still appeared on the gold and silver "Britannia" bullion coins issued annually by the Royal Mint.

After the Roman withdrawal, the term "Britannia" remained in use in Britain and abroad. Latin was ubiquitous amongst native Brythonic Writers and the term continued in the Welsh tradition that developed from it. Writing with variations on the term Britannia (or Prydein in the native language) appeared in many Welsh works such as the Historia Britonum, Armes Prydein and the 12th-century Historia Regum Britanniae, which gained unprecedented popularity throughout western Europe during the High Middle Ages.

A new definitive £2 coin was issued in 2015, with a new image of Britannia. In late 2015, a limited edition (100000 run) £50 coin was produced, bearing the image of Britannia on one side and Queen Elizabeth II on the obverse.

Britain's first road atlas was updated in a series of editions titled from the early 18th into the early 19th centiry using the title Britannia Depicta.