In her early school years, Elisabetta transferred from St-Gertrude Elementary School in Montreal to Jean-Nicolet elementary due to a lack of understanding and communicating in French. A year later, perfectly fluent in French, she was back at St-Gertrude Elementary. Teachers where astonished at the rapidity of her learning the language. She then attended Calixa-Lavallée a French High School where she was part of the theatre group and won for best Actress for her leading role as "Lucretia" in "La Mandragore", the year's theater play. She then graduated in 1999. For the following year, Elisabetta took a year off from school and decided to dedicate her time to several part-time jobs. In 2000 she attended Dawson College to study Creative Arts. In 2001 she transferred to Lasalle College in downtown Montreal where she graduated in Interior Design. She then took several other evening classes such as jewelry design, furniture design and language classes such as Spanish and German at various institutions. She also took many acting workshops training with the best in Montreal, Quebec. She worked as an interior designer creating residential and commercial spaces until 2006 when she decided to dedicate herself to her biggest passion, acting.

Elisabetta gained much recognition in 2006 with her appearance on the reality television series Loft Story, a Big Brother-inspired show based in Montreal. The season aired from January 2006 until April 2006. Elisabetta appeared in 57 episodes. Loft Story was Quebec's first docu-reality series and got tremendous coverage in the press. Elisabetta then appeared on many talks shows. She also had several cameos on various TV shows (such as 9.5 by Angelo Cadet & Lucien Didier) and music videos.

In January 2007, Elisabetta released her first single Feel a remix of the song by Robbie Williams. The song was partly translated in Italian and has a house-trance style. The song featured on Tycoon Records' MC Mario's Mixdown 2007 distributed by Sony.

Based on her reality television appearances, Elisabetta was approached with a book deal by Les Publications Charron & cie. The book talks about her experience on the hit show Loft Story 2, and her sudden success. Journal Intime d'une lofteuse was published in May 2008.

In the short film "Attachment" directed by Kim Barr Elisabetta plays the beautiful girl, one of the victims of a businessman whose addiction to his wireless turns him into a Monster and only a wake up call can stop him. The film was in the official selection of the 2009 Montreal World Film Festival and the Fantasia Film Festival.

Elisabetta also played Carolyn Thacker on The Mountain a movie for NBC directed by Douglas Barr which is also being used as a pilot for a possible series. The Mountain was aired in 2010.

"My name is Sandy" is Elisabetta's first major lead in a feature-length film. The film is inspired by a variety of interviews conducted with local sex-workers. The film stars Elisabetta Fantone as Sandy, an illegal immigrant from France who has been working Manhattan's streets for three years. After a long day's work, she is asked by a client if he can document her for a report he's doing on sex-workers. The tale of a young woman’s descent and experiences in the world of prostitution are heard and seen threw the reportage of her latest client, Francis. "My name is Sandy", directed by Marco Iammatteo and photographed by T.Anthony Gharzouzi.