Gedeon Burkhard was born in Munich, Germany, the son of German Actress Elisabeth von Molo (then Burkhard) and Wolfgang Burkhard, a great-grandson of Aleksandër Moisiu, famous Albanian actor of the 20th century. Gedeon was educated at a boarding school in England and began his acting career in 1979 in the German TV film Tante Maria. His father, Wolfgang Burkhard, is his manager.

During the 1990s, he lived in the U.S.A, working in several productions, but without much recognition. Burkhard married Katjuscha Burkhard (Wladimirowna). in Khimki, only to divorce a few months later. After that, he lived in Vienna for Kommisar Rex for more than five years, before moving to Berlin for work reasons. Burkhard was working in Cologne on the TV series Alarm für Cobra 11 as the detective Chris Ritter, until the end of his contract in November 2007. His character Chris Ritter had a heroic death. He then returned to Berlin, to be close to his daughter and to work in new projects. He said: "For the moment I will dedicate myself again fully to my artistic vagabond life in Berlin". Burkhard appeared in the Quentin Tarantino movie Inglourious Basterds. In February 2009, he was shooting the film "Massel", made for German television. In 2011, he was in Rome, shooting an Italian mini TV series of 6 chapters "Caccia al Re - La Narcotici", with other Italian actor like Stefano Dionisi, Raffaella Rea and Laura Glavan, in which he plays a drug investigator, Daniele Piazza.

In 2011, he competed in the Italian version of "Dancing with the Stars", accompanied by professional Italian Dancer Samanta Togni, in which he danced with his "daughter" Laura Glavan.