She played a homeless character, “The Kid,” on a Christmas episode of Growing Pains. She played Penny Waters, the daughter of fictional former football player Joe Waters on the Showtime comedy series Brothers, which is her longest lasting role. In 1990, a year after Brothers left the air, Todd moved into her next sitcom role as spunky writer-and-aspiring-comedian Kate Griffin on Going Places.

Todd has been married to director/producer Glenn Withrow since 1991. The couple have a daughter, Ivy.

She appeared in seven episodes of Murder, She Wrote, all but one as "Rhoda Markowitz", assistant to Keith Michell's suave sleuth, Dennis Stanton. Todd starred in the feature film The Mooring, which she co-wrote with her husband and daughter. The film was released on DVD, digital download and Video on Demand on February 19, 2013. Todd is the co-founder of the film production company In House Media and also teaches acting classes and privately coaches.

In 2016, Todd was seen starring in Universal's American Girl: Lea to the Rescue. She was cast in The Last Champion, and will executive produce and perform in the film. Her husband, Glenn Withrow, is set to direct the project. He and Todd co-wrote the screenplay along with their daughter, Ivy Withrow, VP of Development for the company. In House Media Film Partners was born when Todd and Withrow were inspired to create a family production company after Withrow's experiences working with Francis Ford Coppola on five films, starting with The Outsiders.

Later roles include Lal, Data's "daughter" on the Star Trek: The Next Generation episode "The Offspring;" Blanche's niece, Lucy, on The Golden Girls episode "Nice and Easy;" the mother in the Disney Channel original movie The Ultimate Christmas Present; Hilda's and Zelda’s cousin Marigold, Amanda's mother, on Sabrina, the Teenage Witch; and as Lizzie's mother, Jo McGuire, on Lizzie McGuire.