After the Old Vic, Holden turned to repertory, where she met her first husband, the actor Edwin Richfield, who appeared in the television series The Buccaneers. They were married in 1952, while they were both appearing in a stage version of The Blue Lamp. They had three children.

Holden was an elegant Actress, notable for her arresting pale blue eyes. She made her West End debut in 1958 in "Speaking of Murder" at St Martin's Theatre, which was followed by "The Tunnel of Love", a farce at the Apollo Theatre.

Holden was heartbroken when her twin brother drowned during the early 1960s. In 1973 her marriage broke down, leaving her with three teenage children to bring up. In 1988 she married Louis Manson, a solicitor and Business man, but she was already in poor health and remained so during her final two decades. In 1999, one of her twin daughters died from a brain tumour, but she remained cheerful and courageous until her own death in 2005. She was survived by her husband, the son Simon, and remaining daughter of her first marriage, and two stepdaughters and four stepsons.