Since moving to Los Angeles, she has appeared in a number of films including And Then Came Lola, Devil Girl and 2 Minutes Later which won her the Best Actress Award at the Tampa International Gay and Lesbian Film Festival. She has also appeared on the stage and her commercial credits include AOL, Southwest Airlines, and PETA. In 2013 Jessica produced Chasseur, written and directed by her frequent collaborator Christopher Soren Kelly, and starring Kelly and Joshua Bitton, which won Best Short at Fly Away Film Festival and Timecode:NOLA. In 2015, she produced and starred opposite Christopher Soren Kelly in the short film Monkeys, for which Kelly also directed. She will again be seen opposite Kelly in two upcoming features, The Tangle and Murder Made Easy.

Graham was born and raised in the Philadelphia area. She is the oldest of three sisters and has a half-brother and two step brothers. Her mother raises and trains Alpacas and also works as a gardener for an all-women’s gardening company. Her stepfather is a carpenter and her father, who died in, worked in an oil refinery. Graham spent part of her childhood living in a 400-year-old house in Ridley State Park without television. Graham is self-taught except for attending The School in Rose Valley from 4th through 6th grade. It was there that Graham did her first real play, Antigone, playing the title role.