Pierre Richard started his career in the theater with Antoine Bourseiller and producing himself in famous cabarets from Paris, where he played his first sketches written with Victor Lanoux. He then began his film career in 1968 in the film Very Happy Alexander directed by Yves Robert. In 1970, he directed his first film Le Distrait, followed by Les Malheurs d'Alfred (1972) and I Don't Know Much, But I'll Say Everything (1973). He worked again with Yves Robert for the film The Tall Blond Man with One Black Shoe (1973) and its sequel The Return of the Tall Blond Man with One Black Shoe (1974), both written by Francis Veber, who then cast him in the main role in his directorial debut, The Toy (1976). Their partnership achieved further success in three successful comedies of the early 1980s, La Chèvre (1981), Les Compères (1983) and Les Fugitifs (1986), which paired Richard with Gérard Depardieu. Richard returned behind the camera to direct On peut toujours rêver (1991) and Droit dans le mur (1997).

Since 1986, Pierre Richard has also become a businessman and winemaker. He owns the restaurant Au pied de chameau in Paris and a 50-hectare vineyard which produces some 80,000 bottles a year (red and rosé) labelled as Château Bel Évêque in Gruissan in the department of Aude.