Edwards hosted a Saturday evening radio show on XFM entitled The Weekender for several years, hosting his last show on 10 January 2009. He also formed part of the BBC presenting team for their coverage of the Reading and Leeds Festival. In 2011 Edwards began hosting E4's Tool Academy, a reality TV show about fed-up girlfriends who have enrolled their underperforming other halves in a school in which "tools become men". During the 2012 Paralympics, Edwards formed part of the Channel 4 commentary team as well as co-presenting That Paralympic Show with Ade Adepitan.

Edwards stated in an interview with the Daily Mail that he has no sense of smell due to sniffing pure ammonia while in school. Edwards supported green organisation Global Cool in 2010 as part of their Traincation campaign, along with his friend George Lamb.

In 2013, Edwards began co-presenting political discussion show Free Speech for BBC Three alongside Tina Daheley. During the 2015 General Election, they presented a series of Free Speech specials.

In December 2015, Edwards began hosting a radio podcast series for Radio Wolfgang called Science(ish), in which he and a group of experts investigate the merits of scientific elements in works of popular culture such as movies, television and literature.

Edwards married Eastenders Actress Emer Kenny in 2016.