She married actor Peter Van Eyck in the 1940s, but the marriage was unsuccessful. Van Eyck was the father of her daughter, Shelley, who was born in 1941. Prior to Ford's trip west to Hollywood she was a member of Orson Welles' Mercury Theatre, and appeared in his film Too Much Johnson (1938), which was considered lost until the rediscovery of footage in 2013. Welles' assistance helped her to land contracts with Columbia Pictures and Warner Bros. studios.

Ford married film star Zachary Scott and they remained together until Scott's death in 1965. Scott adopted Shelley, who took the name Shelley Scott. Zachary Scott reportedly died penniless except for a $100,000 insurance policy he left for his widow.

She starred in the 1976 Broadway play Poor Murderer.

In May 2010 it was reported, originally in The Wall Street Journal, that Ford's estate had been worth $8.4 million, almost all of it in the value of two apartments she owned in the famous apartment building The Dakota in Manhattan, where she died at the age of 98 in 2009. One of the apartments had belonged to her brother Charles, who predeceased her. She bequeathed the apartments to her cook/butler, Indra Tamang, a Nepalese-American whom Charles Henri Ford had brought to New York. Ford's daughter and grandchildren were reportedly disinherited.