Her next release was the Tamil romantic comedy Aaha Kalyanam, an official remake of the 2010 Hindi film Band Baaja Baaraat. Kapoor was cast opposite Nani and learned Tamil and Telugu languages for the film. Upon the release, Kapoor received positive reviews for playing the lead female role. IndiaGlitz called Kapoor's performance "impressive, with her expressions and dialogues perfectly in place with the attitude of her character". According to the Box Office India, the film was an average-grosser.

Kapoor made her film debut with Parineeti Chopra and Sushant Singh Rajput in the 2013 romantic comedy Shuddh Desi Romance, a critical and commercial success. Her performance earned her several awards and nominations, including the Best Female Debut at the 59th Filmfare Awards. In 2014, she ventured into the South Indian film industry with the Tamil and Telugu language romantic comedy Aaha Kalyanam, that proved to be a moderate box-office success and her portrayal of the lead female character was praised.

In 2016, Kapoor appeared in Aditya Chopra's romantic drama Befikre opposite Ranveer Singh. The film, set in Paris, was released on 9 December 2016.The film received negative reviews from critics and became an average grosser at the box office. Shubhra Gupta of The Indian Express describes Vaani's Role as ''You can see Vaani trying for more in a few scenes, but she appears stymied for the most part. Better fleshed-out, she could have been a truly spunky here-and-now leading lady, changing her own gears on love and life.''

Recently in 2017 ,Vaani appeared in a Yash Raj Remake Music Video titled as "Main Yaar Manana Ni", which was extremely hit song.

She signed an untitled movie starring Hrithik Roshan and Tiger Shroff, which will be released in 2019.