After she married Fedderson, Lime left acting to concentrate her time to philanthropy. In the 1950s, she had entertained American troops stationed in Japan. Fedderson and fellow Actress, Sara Buckner O'Meara, who met on the set of The Adventures of Ozzie and Harriet, in which they were both guest stars, launched International Orphans Inc., a charity which built and maintained four orphanages in Japan and five orphanages, a hospital, and a school in Vietnam. Fedderson and O'Meara later devoted their efforts to assist neglected children in the United States and renamed their group, Childhelp, an organization based in Scottsdale, Arizona. The two were also involved in Operation Babylift at the time of the United States evacuation of the former South Vietnam.

She was born Yvonne Glee Lime in Glendale, California, the daughter of a music Teacher who encouraged her to become an Actress. She graduated in 1953 from Glendale High School, having obtained a special permit to attend there, rather than the otherwise assigned Hoover High School. Lime recalls her years at Glendale High School with jubilation:

Lime's first television appearance was on her Future husband's The Millionaire as the character "Eileen" in "The Story of Joy Costello." She appeared in 1956 as Mary Lou Carter in the episode, "The Select Females," of the CBS/Desilu series, The Adventures of Jim Bowie starring Scott Forbes. In 1957, she portrayed Gloria Binks in the Hardy Boys serial, The Mystery of the Ghost Farm. That same year she played a character "Mary" in "A Coney Island Wedding" on the ABC series about the clergy, Crossroads. In 1958, she played "Iris" on "Ladies' Aide", an episode of Jackie Cooper's The People's Choice, which features a talking basset hound, the premise which led two years later to the child "Happy."

In 1957, she was cast in films, in an uncredited part as "Sally" in Elvis Presley's Loving You and in Michael Landon's I Was a Teenage Werewolf, and with top billing in 1958's Dragstrip Riot. She and Don Fedderson had a daughter, Dionne Fedderson; he had seven children from two previous marriages. Don Fedderson produced three popular television series, The Millionaire, My Three Sons, and Family Affair.

From 1959 to 1961, she appeared twice each on two CBS sitcoms, Dwayne Hickman's The Many Loves of Dobie Gillis and Frank Aletter's Bringing Up Buddy. Lime also was cast in episodes of NBC's Wichita Town and Bat Masterson, and on CBS's Gomer Pyle, U.S.M.C. Her last acting role was on My Three Sons as "Linda" in the 1968 episode "The Grandfathers."

From 1960 to 1961, Yvonne Lime had a co-starring role as Sally Day in the 16-episode NBC sitcom, Happy, in which she and Ronnie Burns, the late adopted son of George Burns and Gracie Allen, played owners of a motel in southern California who have a talking baby called "Happy." Lloyd Corrigan and Doris Packer were regulars on the series, which began as a summer replacement in 1960 for The Perry Como Show and thereafter in 1961 for several episodes on the regular NBC schedule. She had also appeared in varying roles from 1956 to 1958 in eleven episodes of The George Burns and Gracie Allen Show.

Yvonne Fedderson and her daughter, Dionne, reside in Paradise Valley, Arizona. She is the author of Miracle Healing: God's Call: Testimonials of Miracles Through Sara Buckner O'Meara, published in 2011.